Title : Human steroid biosynthesis for the oncologist.

Pub. Date : 2012 Feb

PMID : 22222232






1 Functional Relationships(s)
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1 Since then, AIs have become first-line adjuvant therapy for ER breast cancer in postmenopausal women.In late 2010, a trial comparing abiraterone acetate (a 17-hydroxylase/17,20-lyase [CYP17A1] inhibitor) plus prednisone versus prednisone alone in men with castration-resistant prostate cancer (CRPC) previously treated with docetaxel chemotherapy was terminated early because of the survival benefit in the abiraterone acetate arm. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens