Title : Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer.

Pub. Date : 2010 Mar 20

PMID : 20159814






1 Functional Relationships(s)
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1 Abiraterone acetate (AA) is a potent and selective inhibitor of CYP17, which is required for androgen biosynthesis in the testes, adrenal glands, and prostate tissue. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens