Pub. Date : 2010 Mar 20
PMID : 20159824
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. | Abiraterone Acetate | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | PURPOSE: Abiraterone acetate is a prodrug of abiraterone, a selective inhibitor of CYP17, the enzyme catalyst for two essential steps in androgen biosynthesis. | Abiraterone Acetate | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |