Pub. Date : 2009 Jun 15
PMID : 19509232
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Abiraterone acetate is a potent, selective, and orally bioavailable small molecule inhibitor of CYP17, an enzyme that catalyzes two key serial reactions (17 alpha hydroxylase and 17,20 lyase) in androgen and estrogen biosynthesis. | Abiraterone Acetate | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
2 | Biomarker studies, including the analysis of ETS gene fusion status, on patients treated with abiraterone acetate may allow enrichment of patients with a sensitive phenotype in future studies of therapeutics targeting CYP17. | Abiraterone Acetate | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |