Title : Targeting the adrenal gland in castration-resistant prostate cancer: a case for orteronel, a selective CYP-17 17,20-lyase inhibitor.

Pub. Date : 2013 Apr

PMID : 23371447






1 Functional Relationships(s)
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1 Therapeutic CYP17 inhibition by ketoconazole or by the recently approved adrenal inhibitor abiraterone acetate is the only available choice to target this pathway in CRPC. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens