Title : [CYP17A1 inhibitors in prostate cancer: mechanisms of action independent of the androgenic pathway].

Pub. Date : 2013 Oct

PMID : 24314739






1 Functional Relationships(s)
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1 RESULTS: Inhibition of CYP17A1 with abiraterone acetate induces changes in steroid metabolism, whose main component is the reduction of DHEA and androstenedione synthesis. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens