| 1 |
34072728 | In-Silico Evaluation of Genetic Alterations in Ovarian Carcinoma and Therapeutic Efficacy of NSC777201, as a Novel Multi-Target Agent for TTK, NEK2, and CDK1. | 2021 May 31 |
1 |
| 2 |
34126457 | N-acetylgalactosamine-decorated nanoliposomes for targeted delivery of paclitaxel to hepatocellular carcinoma. | 2021 Oct 15 |
1 |
| 3 |
34435645 | Proteasome inhibitors decrease paclitaxel‑induced cell death in nasopharyngeal carcinoma with the accumulation of CDK1/cyclin B1. | 2021 Oct |
5 |
| 4 |
32401925 | Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway. | 2020 |
1 |
| 5 |
32494162 | MiR-153-5p Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Paclitaxel by Inducing G2M Phase Arrest. | 2020 |
1 |
| 6 |
31295843 | Inhibition of Phosphatidylinositol 3-kinase (PI3K) Signaling Synergistically Potentiates Antitumor Efficacy of Paclitaxel and Overcomes Paclitaxel-Mediated Resistance in Cervical Cancer. | 2019 Jul 10 |
2 |
| 7 |
29416675 | Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer. | 2018 Jan 2 |
3 |
| 8 |
28534969 | The Cdc2/Cdk1 inhibitor, purvalanol A, enhances the cytotoxic effects of taxol through Op18/stathmin in non-small cell lung cancer cells in vitro. | 2017 Jul |
9 |
| 9 |
27611665 | Cell Division Cycle 6 Promotes Mitotic Slippage and Contributes to Drug Resistance in Paclitaxel-Treated Cancer Cells. | 2016 |
1 |
| 10 |
26246051 | Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult. | 2015 Nov |
1 |
| 11 |
26442525 | Restoration of paclitaxel resistance by CDK1 intervention in drug-resistant ovarian cancer. | 2015 Dec |
6 |
| 12 |
24180279 | Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)- 1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues. | 2014 |
1 |
| 13 |
24195507 | Cyclin-dependent kinase 1 inhibitor RO3306 promotes mitotic slippage in paclitaxel-treated HepG2 cells. | 2014 |
1 |
| 14 |
24495785 | Phenethyl isothiocyanate and paclitaxel synergistically enhanced apoptosis and alpha-tubulin hyperacetylation in breast cancer cells. | 2014 Feb 5 |
1 |
| 15 |
23628417 | Tumor suppressor BLU promotes paclitaxel antitumor activity by inducing apoptosis through the down-regulation of Bcl-2 expression in tumorigenesis. | 2013 May 24 |
1 |
| 16 |
21821547 | Recurrence risk score based on the specific activity of CDK1 and CDK2 predicts response to neoadjuvant paclitaxel followed by 5-fluorouracil, epirubicin and cyclophosphamide in breast cancers. | 2012 Apr |
1 |
| 17 |
22965228 | Cyclin-dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phosphoregulation of antiapoptotic Bcl-2 proteins. | 2012 Nov 9 |
2 |
| 18 |
22019170 | Paclitaxel induces apoptosis through activation of nuclear protein kinase C-δ and subsequent activation of Golgi associated Cdk1 in human hormone refractory prostate cancer. | 2011 Dec |
3 |
| 19 |
19781537 | Synergistic mitosis-arresting effects of arsenic trioxide and paclitaxel on human malignant lymphocytes. | 2010 Jan 5 |
3 |
| 20 |
19039521 | Bortezomib treatment of ovarian cancer cells mediates endoplasmic reticulum stress, cell cycle arrest, and apoptosis. | 2009 Dec |
1 |
| 21 |
19239702 | Prediction of paclitaxel sensitivity by CDK1 and CDK2 activity in human breast cancer cells. | 2009 |
7 |
| 22 |
19560278 | Stress hormones mediate drug resistance to paclitaxel in human breast cancer cells through a CDK-1-dependent pathway. | 2009 Nov |
3 |
| 23 |
18813780 | Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1. | 2008 Oct |
1 |
| 24 |
16972069 | Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity. | 2007 Feb |
2 |
| 25 |
16639080 | BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance. | 2006 May |
1 |
| 26 |
15590651 | Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappaB and the serine/threonine kinase Akt and is independent of tubulin polymerization. | 2005 Feb 25 |
1 |
| 27 |
15688426 | Novel indication for cancer therapy: Chk1 inhibition sensitizes tumor cells to antimitotics. | 2005 Jul 1 |
2 |
| 28 |
15897904 | Paclitaxel induces the phosphorylation of the eukaryotic translation initiation factor 4E-binding protein 1 through a Cdk1-dependent mechanism. | 2005 Jul 14 |
2 |
| 29 |
16020661 | Cyclin A-associated kinase activity is needed for paclitaxel sensitivity. | 2005 Jul |
1 |
| 30 |
15059905 | Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint. | 2004 Apr 1 |
2 |
| 31 |
15269161 | Cell cycle-dependent antagonistic interactions between paclitaxel and gamma-radiation in combination therapy. | 2004 Jul 15 |
1 |
| 32 |
12973835 | ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression. | 2003 Sep 15 |
2 |
| 33 |
11843726 | Analysis of cell-cycle checkpoint pathways in head and neck cancer cell lines: implications for therapeutic strategies. | 2002 Feb |
1 |
| 34 |
12049736 | Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. | 2002 May |
4 |
| 35 |
12384528 | Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells. | 2002 Oct 15 |
3 |
| 36 |
12478465 | Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe. | 2002 Dec |
1 |
| 37 |
10769641 | Involvement of p21Waf1 in mediating inhibition of paclitaxel-induced apoptosis by epidermal growth factor in MDA-MB-468 human breast cancer cells. | 2000 Jan-Feb |
3 |
| 38 |
10810342 | Induction of senescence-like phenotype and loss of paclitaxel sensitivity after wild-type p53 gene transfection of p53-null human non-small cell lung cancer H358 cells. | 2000 Mar-Apr |
1 |
| 39 |
10956385 | Up-regulation of cdc2 protein during paclitaxel-induced apoptosis. | 2000 Sep 15 |
15 |
| 40 |
11093360 | Flavopiridol, the first cyclin-dependent kinase inhibitor to enter the clinic: current status. | 2000 Dec |
1 |
| 41 |
11225845 | Activation of MAD 2 checkprotein and persistence of cyclin B1/CDC 2 activity associate with paclitaxel-induced apoptosis in human nasopharyngeal carcinoma cells. | 2000 Jun |
3 |
| 42 |
10510942 | Signaling network of paclitaxel-induced apoptosis in the LNCaP prostate cancer cell line. | 1999 Oct |
1 |
| 43 |
10516758 | Bryostatin 1 enhances paclitaxel-induced mitochondrial dysfunction and apoptosis in human leukemia cells (U937) ectopically expressing Bcl-xL. | 1999 Oct |
1 |
| 44 |
10534572 | Molecular effects of taxol and caffeine on pancreatic cancer cells. | 1999 Nov |
2 |
| 45 |
9438385 | Taxol-induced p34cdc2 kinase activation and apoptosis inhibited by 12-O-tetradecanoylphorbol-13-acetate in human breast MCF-7 carcinoma cells. | 1998 Jan |
9 |
| 46 |
9668078 | Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis. | 1998 Jul 24 |
2 |
| 47 |
9721872 | Paclitaxel-induced apoptosis is associated with expression and activation of c-Mos gene product in human ovarian carcinoma SKOV3 cells. | 1998 Aug 15 |
1 |
| 48 |
9844631 | Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. | 1998 Nov |
5 |
| 49 |
9844922 | Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells. | 1998 Dec |
5 |
| 50 |
9230211 | Activation of CDC 25 phosphatase and CDC 2 kinase involved in GL331-induced apoptosis. | 1997 Jul 15 |
2 |