Title : Novel indication for cancer therapy: Chk1 inhibition sensitizes tumor cells to antimitotics.

Pub. Date : 2005 Jul 1

PMID : 15688426






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Chk1 inhibition facilitates paclitaxel-induced M-phase entry by activation of Cdc2 kinase and accumulation of cyclin B1, the required cofactor for Cdc2 kinase activity. Paclitaxel cyclin dependent kinase 1 Homo sapiens
2 Chk1 inhibition facilitates paclitaxel-induced M-phase entry by activation of Cdc2 kinase and accumulation of cyclin B1, the required cofactor for Cdc2 kinase activity. Paclitaxel cyclin dependent kinase 1 Homo sapiens