Pub. Date : 1998 Jul 24
PMID : 9668078
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | The number of mitotic cells was highest at 24 h (82%), then declined as arrested cells progressed into apoptosis, and barely no mitotic cells were present at 48-60 h. The time curves of paclitaxel-induced cyclin B1 accumulation and stimulation of Cdc2/cyclin B1 kinase activity were identical and superimposable to that of M phase arrest. | Paclitaxel | cyclin dependent kinase 1 | Homo sapiens | ||
2 | Immune complex kinase assays in cell-free systems demonstrated that Bcl-2 protein can be a substrate of Cdc2/cyclin B1 kinase isolated from paclitaxel-treated cells arrested in M phase. | Paclitaxel | cyclin dependent kinase 1 | Homo sapiens |