| 1 |
35166127 | d-Allulose Ameliorates Hyperglycemia Through IRE1α Sulfonation-RIDD-Sirt1 Decay Axis in the Skeletal Muscle. | 2022 Apr 18 |
1 |
| 2 |
33393497 | Insulin signaling in health and disease. | 2021 Jan 4 |
1 |
| 3 |
33727228 | Alterations in the Global Proteome and Phosphoproteome in Third Generation EGFR TKI Resistance Reveal Drug Targets to Circumvent Resistance. | 2021 Jun 1 |
1 |
| 4 |
33888713 | Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. | 2021 Apr 22 |
1 |
| 5 |
34157521 | Epidermal growth factor receptor and integrins meet redox signaling through P66shc and Rac1. | 2021 Oct |
1 |
| 6 |
34358366 | Effect of tyrosine kinase inhibitors on cell migration and epithelial-to-mesenchymal transition in Asian head and neck cancer cell lines. | 2021 Nov |
1 |
| 7 |
34532094 | AKT inhibits the phosphorylation level of H2A at Tyr57 via CK2α to promote the progression of gastric cancer. | 2021 Aug |
1 |
| 8 |
31751860 | Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma. | 2020 Jan |
1 |
| 9 |
31819168 | Correction: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential. | 2020 Mar |
1 |
| 10 |
31953320 | A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors. | 2020 Feb 28 |
1 |
| 11 |
32337956 | Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation. | 2020 |
1 |
| 12 |
32346419 | PTEN inhibitor VO-OHpic suppresses TSC2- / - MEFs proliferation by excessively inhibiting autophagy via the PTEN/PRAS40 pathway. | 2020 Jun |
1 |
| 13 |
32823607 | Enforced C-Src Activation Causes Compartmental Dysregulation of PI3K and PTEN Molecules in Lipid Rafts of Tongue Squamous Carcinoma Cells by Attenuating Rac1-Akt-GLUT-1-Mediated Sphingolipid Synthesis. | 2020 Aug 13 |
1 |
| 14 |
33238540 | Src Mediates Epigallocatechin-3-O-Gallate-Elicited Acid Sphingomyelinase Activation. | 2020 Nov 23 |
1 |
| 15 |
33253205 | Alternative AKT2 splicing produces protein lacking the hydrophobic motif regulatory region. | 2020 |
1 |
| 16 |
30944303 | MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression. | 2019 Apr 3 |
3 |
| 17 |
31097679 | Tyrosine nitrations impaired intracellular trafficking of FSHR to the cell surface and FSH-induced Akt-FoxO3a signaling in human granulosa cells. | 2019 May 15 |
1 |
| 18 |
31184863 | Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α. | 2019 Jun 25 |
1 |
| 19 |
31570699 | Aberrant HER3 ligand heregulin-expressing head and neck squamous cell carcinoma is resistant to anti-EGFR antibody cetuximab, but not second-generation EGFR-TKI. | 2019 Sep 30 |
1 |
| 20 |
31614935 | Whole Genome Sequencing of Familial Non-Medullary Thyroid Cancer Identifies Germline Alterations in MAPK/ERK and PI3K/AKT Signaling Pathways. | 2019 Oct 13 |
1 |
| 21 |
31794427 | Ninjurin2 overexpression promotes glioma cell growth. | 2019 Dec 2 |
1 |
| 22 |
28951244 | Tyrosines-740/751 of PDGFRβ contribute to the activation of Akt/Hif1α/TGFβ nexus to drive high glucose-induced glomerular mesangial cell hypertrophy. | 2018 Jan |
2 |
| 23 |
29266303 | Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3. | 2018 Jun |
1 |
| 24 |
29453318 | Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance. | 2018 May |
1 |
| 25 |
29910466 | XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation. | 2018 Jun 18 |
1 |
| 26 |
28082684 | Absence of IQGAP1 Protein Leads to Insulin Resistance. | 2017 Feb 24 |
2 |
| 27 |
28263756 | Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts. | 2017 Apr |
2 |
| 28 |
28486761 | Panitumumab interaction with TAS-102 leads to combinational anticancer effects via blocking of EGFR-mediated tumor response to trifluridine. | 2017 Aug |
2 |
| 29 |
28581009 | Decoding the anticancer activity of VO-clioquinol compound: the mechanism of action and cell death pathways in human osteosarcoma cells. | 2017 Jul 19 |
1 |
| 30 |
28603063 | Overexpression of phosphoprotein phosphatase 2A predicts worse prognosis in patients with breast cancer: a 15-year follow-up. | 2017 Aug |
1 |
| 31 |
29088763 | Overexpression of centromere protein K (CENP-K) gene in hepatocellular carcinoma promote cell proliferation by activating AKT/TP53 signal pathway. | 2017 Sep 26 |
1 |
| 32 |
29371952 | Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma. | 2017 Dec 26 |
1 |
| 33 |
26702053 | Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation. | 2016 Feb 26 |
1 |
| 34 |
26890744 | miR-302 Attenuates Amyloid-β-Induced Neurotoxicity through Activation of Akt Signaling. | 2016 |
1 |
| 35 |
27175625 | Deciphering the effect of an oxovanadium(iv) complex with the flavonoid chrysin (VOChrys) on intracellular cell signalling pathways in an osteosarcoma cell line. | 2016 Aug 1 |
1 |
| 36 |
27294206 | Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells. | 2016 Mar |
1 |
| 37 |
27381982 | Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7. | 2016 Sep |
2 |
| 38 |
27543756 | Role of Herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway. | 2016 Nov |
1 |
| 39 |
24882578 | Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation. | 2015 Apr 9 |
1 |
| 40 |
25257795 | PDGFR-β-activated ACK1-AKT signaling promotes glioma tumorigenesis. | 2015 Apr 15 |
1 |
| 41 |
25631773 | Epstein-Barr virus LMP2A suppresses MHC class II expression by regulating the B-cell transcription factors E47 and PU.1. | 2015 Apr 2 |
1 |
| 42 |
25659802 | GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy. | 2015 Feb 9 |
1 |
| 43 |
25667086 | Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. | 2015 May |
1 |
| 44 |
25784556 | Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1. | 2015 Apr 24 |
1 |
| 45 |
25813876 | Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling. | 2015 Jul |
1 |
| 46 |
26052821 | PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation. | 2015 Aug |
1 |
| 47 |
26267517 | Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome. | 2015 Sep 4 |
1 |
| 48 |
26640543 | Inhibition of focal adhesion kinase induces apoptosis in bladder cancer cells via Src and the phosphatidylinositol 3-kinase/Akt pathway. | 2015 Nov |
1 |
| 49 |
24276246 | Phosphatidylethanolamine-binding protein 4 is associated with breast cancer metastasis through Src-mediated Akt tyrosine phosphorylation. | 2014 Sep 11 |
4 |
| 50 |
24302004 | Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids. | 2014 Jan 15 |
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