Tyrosine

AKT serine/threonine kinase 1 ; Homo sapiens







187 Article(s)
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151 12755958 Cell signalling and gene expression mediated by RET tyrosine kinase. 2003 Jun 1
152 12829832 Putative phosphatidylinositol 3-kinase (PI3K) binding motifs in ovine betaretrovirus Env proteins are not essential for rodent fibroblast transformation and PI3K/Akt activation. 2003 Jul 1
153 12895435 Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for Akt and AP-1. 2003 Jun 1
154 12897063 Angiogenic role of adrenomedullin through activation of Akt, mitogen-activated protein kinase, and focal adhesion kinase in endothelial cells. 2003 Oct 1
155 12911635 Erasure of kinase phosphorylation in astrocytes during oxygen-glucose deprivation is controlled by ATP levels and activation of phosphatases. 2003 Sep 1
156 14662886 Differential activation of formyl peptide receptor-like 1 by peptide ligands. 2003 Dec 15 2
157 11781242 Tyrosine phosphorylation of B-cell adaptor for phosphoinositide 3-kinase is required for Akt activation in response to CD19 engagement. 2002 Jan 15 2
158 11818455 The synthetic chemoattractant peptide, Trp-Lys-Tyr-Met-Val-D-Met, enhances monocyte survival via PKC-dependent Akt activation. 2002 Feb 1
159 11825565 Activation of the PKB/AKT pathway by ICAM-2. 2002 Jan 2
160 12149249 Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase. 2002 Oct 11 9
161 12150951 Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. 2002 Jul 12 1
162 12186904 Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase. 2002 Sep 1
163 12198159 Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling. 2002 Sep 2 2
164 12218049 Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells. 2002 Nov 15 1
165 12354757 Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells. 2002 Dec 6 1
166 12400610 The role of Aktand RAFTK in beta1 integrin mediated survival of precursor B-acute lymphoblastic leukemia cells. 2002 Aug 1
167 11262408 Roles of cell-cell adhesion-dependent tyrosine phosphorylation of Gab-1. 2001 Jun 1 2
168 11287630 A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. 2001 Apr 10 3
169 11312266 The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. 2001 Jun 22 1
170 11438544 Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression. 2001 Sep 7 6
171 11445557 Regulation of Akt/PKB activation by tyrosine phosphorylation. 2001 Aug 24 6
172 11551902 Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt. 2001 Nov 16 2
173 11598110 Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes. 2001 Dec 28 1
174 11607839 Vav proteins, adaptors and cell signaling. 2001 Oct 1 1
175 10652228 Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation. 2000 Feb 5 1
176 10734320 IL-4 regulation of IL-6 production involves Rac/Cdc42- and p38 MAPK-dependent pathways in keratinocytes. 2000 Mar 16 1
177 10764736 The small G-protein Rac mediates depolarization-induced superoxide formation in human endothelial cells. 2000 Jun 23 1
178 10841774 Oxidative stress and vanadate induce tyrosine phosphorylation of phosphoinositide-dependent kinase 1 (PDK1). 2000 Jun 13 1
179 10910908 A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction. 2000 Aug 1 1
180 10995764 Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. 2000 Dec 15 2
181 11002419 Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor. 2000 Sep 14 2
182 11044134 Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway. 2000 Nov 1
183 10092613 Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway. 1999 Apr 2 1
184 10438468 Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways. 1999 Aug 13 1
185 9852043 The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells. 1998 Dec 18 1
186 7774014 The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. 1995 Jun 2 1
187 1833819 A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. 1991 Oct 11 1