Tyrosine

AKT serine/threonine kinase 1 ; Homo sapiens







187 Article(s)
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Pub. Year
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51 24652289 Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation. 2014 May 2 2
52 24741093 Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activity. 2014 Jul 1
53 25309720 Posttranslational regulation of Akt in human cancer. 2014 1
54 25398386 Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression. 2014 Nov 14 1
55 25657827 The P2Y2 Receptor Interacts with VE-Cadherin and VEGF Receptor-2 to Regulate Rac1 Activity in Endothelial Cells. 2014 Dec 1 1
56 23225242 Decreased phosphorylation of Y¹⁴caveolin-1 in endometrial tissue of polycystic ovary syndrome patients may be related with an insulin resistant state in this tissue. 2013 Apr 1
57 23255608 Asymmetric dimethylarginine induces endothelial nitric-oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1. 2013 Mar 1 4
58 23439647 Interaction of constitutive photomorphogenesis 1 protein with protein-tyrosine phosphatase 1B suppresses protein-tyrosine phosphatase 1B activity and enhances insulin signaling. 2013 Apr 12 1
59 23569237 Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells. 2013 Apr 23 1
60 23583449 A crucial role for Lyn in TIMP-1 erythroid cell survival signalling pathway. 2013 May 21 1
61 23673666 Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor. 2013 Jul 5 2
62 23952536 Anti-c-MET Nanobody - a new potential drug in multiple myeloma treatment. 2013 Nov 1
63 23984895 Rational cotargeting of Pim-1 and Akt in prostate cancer. 2013 Aug 1
64 24070612 Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities. 2013 Oct 18 1
65 22247553 Fibronectin induces endothelial cell migration through β1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766. 2012 Mar 2 2
66 22307544 PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics. 2012 Sep 1
67 22322295 Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. 2012 Apr 1
68 22379109 The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration. 2012 Apr 2
69 22624709 SMIP-016 in action: CD37 as a death receptor. 2012 May 15 1
70 22766331 Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways. 2012 Aug 1
71 22820502 Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling. 2012 Nov 1
72 22962253 Estrogens and PTP1B function in a novel pathway to regulate aromatase enzymatic activity in breast cancer cells. 2012 Nov 1
73 23342251 ERBB3 (HER3) is a key sensor in the regulation of ERBB-mediated signaling in both low and high ERBB2 (HER2) expressing cancer cells. 2012 Aug 1
74 21111731 p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator-induced lung injury. 2011 Apr 1 1
75 21498522 Signalling by insulin and IGF receptors: supporting acts and new players. 2011 Aug 1
76 21807000 Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR. 2011 Sep 12 1
77 21954290 Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration. 2011 Sep 27 1
78 22174934 Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium. 2011 1
79 19815813 Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy. 2010 Jan 1
80 20071559 Progesterone inhibits glucose uptake by affecting diverse steps of insulin signaling in 3T3-L1 adipocytes. 2010 Apr 1
81 20127027 Lewis(y) antigen stimulates the growth of ovarian cancer cells via regulation of the epidermal growth factor receptor pathway. 2010 Mar 1
82 20298531 Methylnaltrexone potentiates the anti-angiogenic effects of mTOR inhibitors. 2010 Feb 19 2
83 20383279 Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms. 2010 Apr 7 3
84 20432460 Shepherding AKT and androgen receptor by Ack1 tyrosine kinase. 2010 Aug 1
85 20473365 Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating Cells. 2010 Mar 1 1
86 20643654 PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival. 2010 Sep 17 1
87 21122136 The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac. 2010 Dec 1 3
88 22011639 Post-burn hepatic insulin resistance is associated with endoplasmic reticulum (ER) stress. 2010 Mar 1
89 22137642 Regulation and differential role of the tissue factor isoforms in cardiovascular biology. 2010 Aug 1
90 18981215 Dual functions of Dab1 during brain development. 2009 Jan 2
91 19015244 A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis. 2009 Jan 1
92 19116273 Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells. 2009 Jan 6 1
93 19154417 Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor. 2009 Mar 1
94 19167484 Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity. 2009 May 1
95 19305428 The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants. 2009 Apr 23 1
96 19473962 Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis. 2009 Jul 24 1
97 19477675 [In vitro capacitation]. 2009 Jun 1
98 19561085 Silencing of ErbB3/ErbB2 signaling by immunoglobulin-like Necl-2. 2009 Aug 28 2
99 19633358 The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. 2009 Sep 18 1
100 19804359 EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells. 2009 Dec 1