Title : Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α.

Pub. Date : 2019 Jun 25

PMID : 31184863






1 Functional Relationships(s)
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1 Upon FGFR activation, FRS2alpha undergoes phosphorylation on multiple tyrosines, triggering recruitment of the adaptor Grb2 and the tyrosine phosphatase Shp2, resulting in stimulation of PI3K/AKT and MAPK signaling pathways. Tyrosine AKT serine/threonine kinase 1 Homo sapiens