Title : PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation.

Pub. Date : 2015 Aug

PMID : 26052821






1 Functional Relationships(s)
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1 We showed that the withdrawal of PI3K/AKT signaling was associated to NOTCH1 phosphorylation in tyrosine residues and monoubiquitination of NOTCH1 detected by Ubiquitin capture assay. Tyrosine AKT serine/threonine kinase 1 Homo sapiens