Title : Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma.

Pub. Date : 2017 Dec 26

PMID : 29371952






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Co-immunoprecipitation and mass spectrometry studies identified IQ motif containing GTPase activating protein 1 (IQGAP1) as a PTPROt binding partner, and PTPROt reduced tyrosine phosphorylation of IQGAP1, providing a link to AKT activity. Tyrosine AKT serine/threonine kinase 1 Homo sapiens