Title : Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation.

Pub. Date : 2015 Apr 9

PMID : 24882578






1 Functional Relationships(s)
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1 Thus, our present findings strongly indicate that the tyrosine phosphorylation of CD133, which is dephosphorylated by PTPRK, regulates AKT signaling and has a critical role in colon cancer progression. Tyrosine AKT serine/threonine kinase 1 Homo sapiens