Title : Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1.

Pub. Date : 2015 Apr 24

PMID : 25784556






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 They provide internal feedback, mediated by Ser(P)(473)-AKT, Ser(P)(401)-GATA2, and nuclear GATA2, which links the opposing effects of serine and tyrosine phosphorylations of IRS1 and can modulate insulin responsiveness. Tyrosine AKT serine/threonine kinase 1 Homo sapiens