Title : Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7.

Pub. Date : 2016 Sep

PMID : 27381982






2 Functional Relationships(s)
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1 Here, we found that following B-cell receptor (BCR)-induced tyrosine phosphorylation of the cytoplasmic tyrosine kinase SYK and the adaptor BLNK, the AKT/PKB enzyme strongly induced BLNK (>100-fold) and SYK (>100-fold) serine/threonine phosphorylation (pS/pT). Tyrosine AKT serine/threonine kinase 1 Homo sapiens
2 Here, we found that following B-cell receptor (BCR)-induced tyrosine phosphorylation of the cytoplasmic tyrosine kinase SYK and the adaptor BLNK, the AKT/PKB enzyme strongly induced BLNK (>100-fold) and SYK (>100-fold) serine/threonine phosphorylation (pS/pT). Tyrosine AKT serine/threonine kinase 1 Homo sapiens