Title : Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells.

Pub. Date : 2016 Mar

PMID : 27294206






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BEZ235 affects PI3K/Akt/mTOR signaling pathway by increasing the phosphorylation of AKT at Ser(473) and RAS/RAF/MEK/ERK pathway by decreasing the phosphorylation of ERK at Tyr(204). Tyrosine AKT serine/threonine kinase 1 Homo sapiens