Title : Meta-analysis of P53 expression and sensitivity to platinum-based chemotherapy in patients with non-small cell lung cancer.

Pub. Date : 2021 Feb 5

PMID : 33592864






4 Functional Relationships(s)
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1 Meta-analysis of P53 expression and sensitivity to platinum-based chemotherapy in patients with non-small cell lung cancer. Platinum tumor protein p53 Homo sapiens
2 This study aims to explore the correlation between p53 expression and sensitivity to platinum-based chemotherapy in patients with NSCLC. Platinum tumor protein p53 Homo sapiens
3 METHODS: Pubmed, Web of Science, EMBASE, CNKI, China Wanfang databases were searched for studies on the relationship between the p53 expression and the chemosensitivity to platinum drugs in patients with NSCLC. Platinum tumor protein p53 Homo sapiens
4 CONCLUSION: Patients with p53 negative expression is more sensitive to platinum-based chemotherapy than those with p53 positive expression in NSCLC, especially in advanced NSCLC. Platinum tumor protein p53 Homo sapiens