Pub. Date : 2016
PMID : 27313779
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Platinum increased p53 in a dose-dependent and time-dependent manner. | Platinum | tumor protein p53 | Homo sapiens |
2 | Knockdown of p53 significantly decreased sensitivity to platinum in 3D cultures. | Platinum | tumor protein p53 | Homo sapiens |
3 | Taken together, our results suggest that p53 is involved in a 3D architecture-mediated decrease in chemosensitivity to platinum in colon cancer. | Platinum | tumor protein p53 | Homo sapiens |