Pub. Date : 2019 Dec
PMID : 31798724
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | CisPt decreased p53 protein phosphorylation in FaDu cells, but increased it in PE/CA-PJ49 cells. | Platinum | tumor protein p53 | Homo sapiens |
2 | In this regard the CisPt treatment suggested that p53 phosphorylation is ERK1/2 independent in FaDu cells having a p53 gene deletion and ERK1/2 dependent in PE/CA-PJ49 cells having a p53 gene amplification. | Platinum | tumor protein p53 | Homo sapiens |
3 | In this regard the CisPt treatment suggested that p53 phosphorylation is ERK1/2 independent in FaDu cells having a p53 gene deletion and ERK1/2 dependent in PE/CA-PJ49 cells having a p53 gene amplification. | Platinum | tumor protein p53 | Homo sapiens |
4 | In this regard the CisPt treatment suggested that p53 phosphorylation is ERK1/2 independent in FaDu cells having a p53 gene deletion and ERK1/2 dependent in PE/CA-PJ49 cells having a p53 gene amplification. | Platinum | tumor protein p53 | Homo sapiens |
5 | Moreover, in both tumor cell lines our results support the involvement of p53 phosphorylation-ERK1/2 activation-dependent in the apoptosis induced by combined treatments (CisPt and CRM). | Platinum | tumor protein p53 | Homo sapiens |