| 1 |
32295912 | Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways. | 2020 Jun 16 |
1 |
| 2 |
31549971 | The role of JAK inhibitors in multiple myeloma. | 2019 Sep |
1 |
| 3 |
29127481 | Expression of Janus Kinase 1 in vitiligo & psoriasis before and after narrow band UVB: a case-control study. | 2018 Jan |
1 |
| 4 |
29761158 | Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer. | 2018 |
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| 5 |
29789426 | JAK1-mediated Sirt1 phosphorylation functions as a negative feedback of the JAK1-STAT3 pathway. | 2018 Jul 13 |
2 |
| 6 |
29870712 | A hispanolone-derived diterpenoid inhibits M2-Macrophage polarization in vitro via JAK/STAT and attenuates chitin induced inflammation in vivo. | 2018 Aug |
1 |
| 7 |
26705936 | Tumor associated macrophages provide the survival resistance of tumor cells to hypoxic microenvironmental condition through IL-6 receptor-mediated signals. | 2017 Jan |
1 |
| 8 |
27799566 | Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma. | 2016 Nov 15 |
1 |
| 9 |
26231159 | Discovery of Tyk2 inhibitors via the virtual site-directed fragment-based drug design. | 2015 Sep 15 |
1 |
| 10 |
26232434 | Parafibromin Is a Component of IFN-γ-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1. | 2015 Sep 15 |
1 |
| 11 |
23236554 | JAK kinases are required for the bacterial RNA and poly I:C induced tyrosine phosphorylation of PKR. | 2013 |
1 |
| 12 |
24082147 | STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor. | 2013 Oct 15 |
1 |
| 13 |
22402124 | JAK-STAT and JAK-PI3K-mTORC1 pathways regulate telomerase transcriptionally and posttranslationally in ATL cells. | 2012 May |
1 |
| 14 |
22528658 | Structural basis of interleukin-5 dimer recognition by its α receptor. | 2012 Jun |
1 |
| 15 |
22763125 | Tyrosine phosphatase PTP-MEG2 negatively regulates vascular endothelial growth factor receptor signaling and function in endothelial cells. | 2012 Sep 1 |
3 |
| 16 |
22961117 | Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin. | 2012 Nov |
1 |
| 17 |
21216930 | JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling. | 2011 Mar |
1 |
| 18 |
21277633 | IL-4 and IL-13 suppress prostaglandins production in human follicular dendritic cells by repressing COX-2 and mPGES-1 expression through JAK1 and STAT6. | 2011 Mar |
1 |
| 19 |
21625597 | Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation. | 2011 |
1 |
| 20 |
21679692 | The tight junction protein ZO-2 and Janus kinase 1 mediate intercellular communications in vascular smooth muscle cells. | 2011 Jul 8 |
2 |
| 21 |
19945455 | STAT1, STAT3 and p38MAPK are involved in the apoptotic effect induced by a chimeric cyclic interferon-alpha2b peptide. | 2010 Feb 15 |
1 |
| 22 |
20006573 | Tumor Necrosis Factor alpha (TNFalpha) regulates CD40 expression through SMAR1 phosphorylation. | 2010 Jan 8 |
1 |
| 23 |
20672017 | A Phosphotyrosine Proteomic Screen Identifies Multiple Tyrosine Kinase Signaling Pathways Aberrantly Activated in Malignant Mesothelioma. | 2010 May 1 |
1 |
| 24 |
18922133 | Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors. | 2009 Feb 1 |
1 |
| 25 |
19014879 | Interferon alpha increases metalloproteinase-13 gene expression through a polyomavirus enhancer activator 3-dependent pathway in hepatic stellate cells. | 2009 Jan |
1 |
| 26 |
19139102 | Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers. | 2009 Mar 13 |
1 |
| 27 |
19231233 | Cytokine production through PKC/p38 signaling pathways, not through JAK/STAT1 pathway, in mast cells stimulated with IFNgamma. | 2009 Apr |
2 |
| 28 |
18281483 | Differential effects of interleukin-2 and interleukin-15 versus interleukin-21 on CD4+ cutaneous T-cell lymphoma cells. | 2008 Feb 15 |
1 |
| 29 |
18346458 | Computational analyses of JAK1 kinase domain: subtle changes in the catalytic cleft influence inhibitor specificity. | 2008 May 23 |
1 |
| 30 |
18596134 | 15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells. | 2008 Dec |
1 |
| 31 |
18682290 | Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway. | 2008 Nov |
2 |
| 32 |
17290288 | Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2. | 2007 Mar |
2 |
| 33 |
17550976 | Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways. | 2007 Sep |
3 |
| 34 |
17703129 | Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling. | 2007 Aug |
1 |
| 35 |
18052729 | Cross-inhibition of interferon-induced signals by GM-CSF through a block in Stat1 activation. | 2007 Nov |
1 |
| 36 |
16595158 | Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway. | 2006 Aug |
1 |
| 37 |
15659558 | Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography. | 2005 Jun |
1 |
| 38 |
16324217 | Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells. | 2005 Dec 2 |
1 |
| 39 |
14647450 | A role for Janus kinases in crosstalk between ErbB3 and the interferon-alpha signaling complex in myeloma cells. | 2004 Feb 12 |
1 |
| 40 |
14978237 | Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1. | 2004 Mar |
3 |
| 41 |
12551917 | YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling. | 2003 Apr 4 |
3 |
| 42 |
12559972 | Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide. | 2003 Feb 1 |
2 |
| 43 |
12738762 | Fer is a downstream effector of insulin and mediates the activation of signal transducer and activator of transcription 3 in myogenic cells. | 2003 Aug |
1 |
| 44 |
12771930 | A novel IL-10 signalling mechanism regulates TIMP-1 expression in human prostate tumour cells. | 2003 May 19 |
1 |
| 45 |
12802285 | IL-10 signaling via IL-10E1 is dependent on tyrosine phosphorylation in the IL-10R alpha chain in human primary prostate cancer cell lines. | 2003 Jun 12 |
1 |
| 46 |
14555918 | The role of signal transducers and activators of transcription in T inflammatory bowel diseases. | 2003 Sep |
1 |
| 47 |
11882386 | Activation and inactivation of signal transducers and activators of transcription by ciliary neurotrophic factor in neuroblastoma cells. | 2002 May |
1 |
| 48 |
11960349 | Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-beta1 is mediated by caspase-dependent and -independent processes. | 2002 Apr |
1 |
| 49 |
12018856 | Increased serine phosphorylation and activation of STAT1 by oncogenic Ras transfection. | 2002 Apr 30 |
1 |
| 50 |
12177620 | Constitutive activation of Jak/STAT proteins in Epstein-Barr virus-infected B-cell lines from patients with posttransplant lymphoproliferative disorder. | 2002 Aug 15 |
2 |