Title : Computational analyses of JAK1 kinase domain: subtle changes in the catalytic cleft influence inhibitor specificity.

Pub. Date : 2008 May 23

PMID : 18346458






1 Functional Relationships(s)
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1 Furthermore, in-silico mutagenesis of these two residues back to Asp and Tyr enabled Jak1 to accommodate WHI-P131. Tyrosine Janus kinase 1 Homo sapiens