Title : IL-4 and IL-13 suppress prostaglandins production in human follicular dendritic cells by repressing COX-2 and mPGES-1 expression through JAK1 and STAT6.

Pub. Date : 2011 Mar

PMID : 21277633

1 Functional Relationships(s)
Compound Name
Protein Name
1 Although IL-4 induced tyrosine phosphorylation of JAK1 and TYK2, RNA interference experiments revealed that only JAK1 was responsible for the IL-4-stimulated STAT6 phosphorylation. Tyrosine Janus kinase 1 Homo sapiens