Title : Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors.

Pub. Date : 2009 Feb 1

PMID : 18922133






1 Functional Relationships(s)
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1 In addition to their role in phosphorylation of receptor tyrosine residues and downstream signalling substrates, JAKs have recently been implicated in controlling expression of cytokine receptors, predominantly by masking critical motifs involved in endocytosis and lysosomal targeting. Tyrosine Janus kinase 1 Homo sapiens