Title : JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling.

Pub. Date : 2011 Mar

PMID : 21216930






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inhibition of JAK1 with small molecules or RNA interference resulted in loss of STAT3 tyrosine phosphorylation and inhibition of cell growth. Tyrosine Janus kinase 1 Homo sapiens