Title : Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway.

Pub. Date : 2006 Aug

PMID : 16595158

1 Functional Relationships(s)
Compound Name
Protein Name
1 This was accomplished by preventing the IFN-alpha-induced tyrosine phosphorylation of STAT-1 and STAT-2 through the inactivation of the upstream receptor associated tyrosine kinases, JAK-1 and Tyk-2. Tyrosine Janus kinase 1 Homo sapiens