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2 | 9651337 | Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. | J Biol Chem | 1998 Jul 10 |
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3 | 9743501 | Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. | Science | 1998 Sep 18 |
2 |
4 | 9926932 | ASK1 mediates apoptotic cell death induced by genotoxic stress. | Oncogene | 1999 Jan 7 |
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5 | 10411906 | Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. | Proc Natl Acad Sci U S A | 1999 Jul 20 |
6 |
6 | 10567572 | BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. | Mol Cell Biol | 1999 Dec |
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7 | 10688666 | Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin. | Mol Cell Biol | 2000 Mar |
3 |
8 | 10849426 | Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation. | J Biol Chem | 2000 Aug 25 |
4 |
9 | 10986282 | Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. | J Biol Chem | 2000 Dec 22 |
2 |
10 | 11003656 | Inhibition of Daxx-mediated apoptosis by heat shock protein 27. | Mol Cell Biol | 2000 Oct |
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11 | 11029458 | Apoptosis signal-regulating kinase 1 (ASK1) is an intracellular inducer of keratinocyte differentiation. | J Biol Chem | 2001 Jan 12 |
1 |
12 | 11096076 | Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1. | J Biol Chem | 2001 Feb 23 |
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13 | 11154276 | Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. | Mol Cell Biol | 2001 Feb |
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14 | 11193028 | The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis. | Ann N Y Acad Sci | 2000 |
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15 | 11243879 | ASK1-signaling promotes c-Myc protein stability during apoptosis. | Biochem Biophys Res Commun | 2001 Mar |
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16 | 11495919 | Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm. | J Biol Chem | 2001 Oct 19 |
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17 | 11498280 | Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process. | Free Radic Biol Med | 2001 Aug 15 |
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18 | 11597122 | Quercetin abrogates taxol-mediated signaling by inhibiting multiple kinases. | Exp Cell Res | 2001 Oct 15 |
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19 | 11598801 | ASK1 resistant neuroblastoma is deficient in activation of p38 kinase. | Cell Death Differ | 2001 Oct |
4 |
20 | 11689443 | Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress. | EMBO J | 2001 Nov 1 |
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21 | 11709494 | Selenite suppresses hydrogen peroxide-induced cell apoptosis through inhibition of ASK1/JNK and activation of PI3-K/Akt pathways. | FASEB J | 2002 Jan |
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22 | 11920685 | Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. | J Cell Physiol | 2002 Apr |
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23 | 12050113 | ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. | Genes Dev | 2002 Jun 1 |
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24 | 12052825 | MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species. | J Biol Chem | 2002 Aug 16 |
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25 | 12089063 | Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. | Circ Res | 2002 Jun 28 |
10 |
26 | 12132586 | Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes. | Mol Cells | 2002 Jun 30 |
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27 | 12189133 | Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade. | J Biol Chem | 2002 Oct 25 |
1 |
28 | 12206715 | Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis. | Biochem J | 2002 Dec 15 |
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29 | 12244106 | Role of glutaredoxin in metabolic oxidative stress. Glutaredoxin as a sensor of oxidative stress mediated by H2O2. | J Biol Chem | 2002 Nov 29 |
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30 | 12424221 | Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway. | FASEB J | 2003 Jan |
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31 | 12435809 | Enhancement of metabolic oxidative stress-induced cytotoxicity by the thioredoxin inhibitor 1-methylpropyl 2-imidazolyl disulfide is mediated through the ASK1-SEK1-JNK1 pathway. | Mol Pharmacol | 2002 Dec |
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32 | 12470897 | Dose effect of oxidative stress on signal transduction in aging. | Mech Ageing Dev | 2002 Nov |
2 |
33 | 12556535 | Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1). | J Biol Chem | 2003 Apr 11 |
1 |
34 | 12623859 | Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates nitric oxide-induced activator protein-1 activation in human bronchial epithelial cells. | Am J Respir Crit Care Med | 2003 Mar 15 |
1 |
35 | 12672819 | The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating kinase 1 and nuclear factor-kappa B. | J Biol Chem | 2003 Jun 6 |
1 |
36 | 12697749 | AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. | J Biol Chem | 2003 Jun 27 |
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37 | 12723971 | Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1. | Biochem J | 2003 Aug 1 |
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38 | 12801522 | S-nitrosylation of thioredoxin mediates activation of apoptosis signal-regulating kinase 1. | Arch Biochem Biophys | 2003 Jul 1 |
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39 | 12813029 | AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3. | J Clin Invest | 2003 Jun |
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40 | 12819028 | ASK1 associates with troponin T and induces troponin T phosphorylation and contractile dysfunction in cardiomyocytes. | Am J Pathol | 2003 Jul |
3 |
41 | 12820963 | Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1). | Mol Cell | 2003 Jun |
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42 | 12858332 | Effect of glucose concentration on activation of the ASK1-SEK1-JNK1 signal transduction pathway. | J Cell Biochem | 2003 Jul 1 |
6 |
43 | 12869527 | Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons. | J Biochem | 2003 Jun |
2 |
44 | 14500571 | Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines. | Endocrinology | 2004 Jan |
6 |
45 | 14505347 | Catalase, but not MnSOD, inhibits glucose deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: hydrogen peroxide as a major second messenger of metabolic oxidative stress. | J Cell Biochem | 2003 Oct 1 |
5 |
46 | 14629743 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced activation of mitogen-activated protein kinase signaling pathway in Jurkat T cells. | Pharmacol Toxicol | 2003 Oct |
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47 | 14668338 | Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism. | J Biol Chem | 2004 Feb 27 |
5 |
48 | 14668614 | Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. | Crit Care Med | 2003 Dec |
3 |
49 | 14720501 | Ebselen inhibits tumor necrosis factor-alpha-induced c-Jun N-terminal kinase activation and adhesion molecule expression in endothelial cells. | Exp Cell Res | 2004 Jan 1 |
2 |
50 | 14761963 | Positive regulation of apoptosis signal-regulating kinase 1 by hD53L1. | J Biol Chem | 2004 Apr 16 |
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