Pub. Date : 2003 Dec
PMID : 14668614
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. | Hydrogen Peroxide | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 2 | MEASUREMENTS AND MAIN RESULTS: The results showed that H2O2 induced ASK1 phosphorylation and concomitantly p38 MAPK and JNK phosphorylation as well as induced caspase-3 activation in pulmonary vascular endothelial cells. | Hydrogen Peroxide | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 3 | CONCLUSION: ASK1-p38 MAPK/JNK cascade regulates apoptosis of H2O2-stimulated human pulmonary vascular endothelial cells. | Hydrogen Peroxide | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |