Title : Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1.

Pub. Date : 2001 Feb

PMID : 11154276






4 Functional Relationships(s)
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Protein Name
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1 Akt decreased ASK1 kinase activity stimulated by both oxidative stress and overexpression in 293 cells by phosphorylating a consensus Akt site at serine 83 of ASK1. Serine mitogen-activated protein kinase kinase kinase 5 Homo sapiens
2 Akt decreased ASK1 kinase activity stimulated by both oxidative stress and overexpression in 293 cells by phosphorylating a consensus Akt site at serine 83 of ASK1. Serine mitogen-activated protein kinase kinase kinase 5 Homo sapiens
3 Finally, activation of the PI3-K/Akt pathway reduced apoptosis induced by ASK1 in a manner dependent on phosphorylation of serine 83 of ASK1. Serine mitogen-activated protein kinase kinase kinase 5 Homo sapiens
4 Finally, activation of the PI3-K/Akt pathway reduced apoptosis induced by ASK1 in a manner dependent on phosphorylation of serine 83 of ASK1. Serine mitogen-activated protein kinase kinase kinase 5 Homo sapiens