Pub. Date : 2003 Jan
PMID : 12424221
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GSH ethyl ester, a precursor of GSH, by counteracting intracellular mixed disulfide formation, canceled both p38 MAPK activation and GSSG-mediated apoptosis via inhibition of thioredoxin oxidation and stabilization of thioredoxin/ASK1 complex, whereas, blockage of p38 MAPK by specific inhibitor SB 203580 allowed apoptosis at a very reduced extent. | S-ethyl glutathione | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 2 | GSH ethyl ester, a precursor of GSH, by counteracting intracellular mixed disulfide formation, canceled both p38 MAPK activation and GSSG-mediated apoptosis via inhibition of thioredoxin oxidation and stabilization of thioredoxin/ASK1 complex, whereas, blockage of p38 MAPK by specific inhibitor SB 203580 allowed apoptosis at a very reduced extent. | Glutathione | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |