Title : Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation.

Pub. Date : 2000 Aug 25

PMID : 10849426






4 Functional Relationships(s)
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1 We found that benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl ketone (zVAD-fmk), a broad-spectrum caspase inhibitor, mostly inhibited ASK1-induced cell death, suggesting that caspases are required for ASK1-induced apoptosis. Caspase Inhibitor VI mitogen-activated protein kinase kinase kinase 5 Homo sapiens
2 We found that benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl ketone (zVAD-fmk), a broad-spectrum caspase inhibitor, mostly inhibited ASK1-induced cell death, suggesting that caspases are required for ASK1-induced apoptosis. Caspase Inhibitor VI mitogen-activated protein kinase kinase kinase 5 Homo sapiens
3 We found that benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl ketone (zVAD-fmk), a broad-spectrum caspase inhibitor, mostly inhibited ASK1-induced cell death, suggesting that caspases are required for ASK1-induced apoptosis. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone mitogen-activated protein kinase kinase kinase 5 Homo sapiens
4 We found that benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl ketone (zVAD-fmk), a broad-spectrum caspase inhibitor, mostly inhibited ASK1-induced cell death, suggesting that caspases are required for ASK1-induced apoptosis. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone mitogen-activated protein kinase kinase kinase 5 Homo sapiens