solute carrier family 22 member 8 ; Rattus norvegicus






173 Article(s)
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1 10224140 Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain. J Biol Chem 1999 May 7 10
2 10954042 Regulation by protein kinase C of organic anion transport driven by rat organic anion transporter 3 (rOAT3). Life Sci 2000 10
3 11331016 Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3. Biochemistry 2001 May 8 12
4 11504818 Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells. J Pharmacol Exp Ther 2001 Sep 1
5 11779196 Differential gene expression of organic anion transporters in male and female rats. Biochem Biophys Res Commun 2002 Jan 11 1
6 11861777 Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. J Pharmacol Exp Ther 2002 Mar 15
7 11879818 Sex hormone-regulated renal transport of perfluorooctanoic acid. Chem Biol Interact 2002 Mar 20 2
8 11912243 Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney. J Am Soc Nephrol 2002 Apr 1
9 11961115 Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus. Mol Pharmacol 2002 May 4
10 11967025 Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney. Kidney Int 2002 May 6
11 12005172 Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1. Life Sci 2002 Mar 8 14
12 12089366 Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity. J Am Soc Nephrol 2002 Jul 4
13 12102636 Role of aromatic transmembrane residues of the organic anion transporter, rOAT3, in substrate recognition. Biochemistry 2002 Jul 16 18
14 12237339 Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1. Mol Pharmacol 2002 Oct 3
15 12358729 Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain. J Neurochem 2002 Oct 11
16 12488248 Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient. Am J Physiol Renal Physiol 2003 Apr 8
17 12524175 Implication of Trip15/CSN2 in early stage of neuronal differentiation of P19 embryonal carcinoma cells. Brain Res Dev Brain Res 2003 Jan 10 1
18 12606766 Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells. Mol Pharmacol 2003 Mar 4
19 12659717 Subchronic oral toxicity study on the three flavouring substances: octan-3-ol, 2-methylcrotonic acid and oct-3-yl 2-methylcrotonate in Wistar rats. Food Chem Toxicol 2003 May 4
20 12660303 Contribution of organic anion transporters to the renal uptake of anionic compounds and nucleoside derivatives in rat. J Pharmacol Exp Ther 2003 Jun 15
21 12679720 Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. J Cereb Blood Flow Metab 2003 Apr 12
22 12684544 Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier. J Pharmacol Exp Ther 2003 Jul 13
23 12954363 Major role of organic anion transporters in the uptake of phenolsulfonphthalein in the kidney. Eur J Pharmacol 2003 Aug 15 4
24 14675047 Characterization of uremic toxin transport by organic anion transporters in the kidney. Kidney Int 2004 Jan 1
25 14722319 Quantitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier. J Pharmacol Exp Ther 2004 Apr 4
26 14978359 Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. J Pharmacol Sci 2004 Feb 2
27 15010355 Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition. Am J Physiol Renal Physiol 2004 Jul 1
28 15213250 The role of advanced glycation in reduced organic cation transport associated with experimental diabetes. J Pharmacol Exp Ther 2004 Nov 1
29 15284287 The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules. J Am Soc Nephrol 2004 Aug 4
30 15287899 Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs. J Neurochem 2004 Aug 10
31 15292460 Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier. J Pharmacol Exp Ther 2004 Dec 2
32 15319347 Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3. Drug Metab Dispos 2004 Sep 8
33 15389674 Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroid plexus. J Pharm Sci 2004 Nov 10
34 15795901 Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; comparison of gene expression between the blood-brain and -retinal barriers. J Cell Physiol 2005 Sep 6
35 15801548 Renal elimination of a novel and potent alphavbeta3 integrin antagonist in animals. Xenobiotica 2004 Nov-Dec 2
36 15846470 Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats. Pharm Res 2005 Apr 4
37 15878738 Altered renal elimination of organic anions in rats with chronic renal failure. Biochim Biophys Acta 2005 Apr 15 2
38 15900017 Functional involvement of rat organic anion transporter 2 (Slc22a7) in the hepatic uptake of the nonsteroidal anti-inflammatory drug ketoprofen. Drug Metab Dispos 2005 Aug 5
39 15958719 Multiple components of 2,4-dichlorophenoxyacetic acid uptake by rat choroid plexus. J Pharmacol Exp Ther 2005 Oct 7
40 16006492 A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters. J Pharmacol Exp Ther 2005 Oct 6
41 16036570 Evidence for rat organic anion transporter 3 association with caveolin-1 in rat kidney. IUBMB Life 2005 Feb 1
42 16258993 Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium. J Pharm Sci 2005 Dec 3
43 16316345 Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction. Kidney Int 2005 Dec 2
44 16338963 Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3. J Am Soc Nephrol 2006 Jan 5
45 16445853 Involvement of organic anion transporters in the efflux of uremic toxins across the blood-brain barrier. J Neurochem 2006 Feb 1
46 16581093 Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain. Neuropharmacology 2006 Jun 4
47 16612331 Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells. Kidney Int 2006 May 1
48 16628676 Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction. Hepatology 2006 May 3
49 16925582 Effect of methotrexate treatment on expression levels of multidrug resistance protein 2, breast cancer resistance protein and organic anion transporters Oat1, Oat2 and Oat3 in rats. Cancer Sci 2006 Nov 3
50 16928864 Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci 2006 Aug 23 4