Pub. Date : 2001 May 8
PMID : 11331016
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3. | Arginine | solute carrier family 22 member 8 | Rattus norvegicus |
| 2 | Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3. | Lysine | solute carrier family 22 member 8 | Rattus norvegicus |
| 3 | The uptakes of p-aminohippurate (PAH), estrone sulfate, and ochratoxin A were approximately 10-, approximately 48-, and approximately 32-fold enhanced in oocytes expressing rOAT3 and were only approximately 2-, approximately 6-, and approximately 5-fold enhanced for R454D. | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 4 | The uptakes of p-aminohippurate (PAH), estrone sulfate, and ochratoxin A were approximately 10-, approximately 48-, and approximately 32-fold enhanced in oocytes expressing rOAT3 and were only approximately 2-, approximately 6-, and approximately 5-fold enhanced for R454D. | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 5 | The uptakes of p-aminohippurate (PAH), estrone sulfate, and ochratoxin A were approximately 10-, approximately 48-, and approximately 32-fold enhanced in oocytes expressing rOAT3 and were only approximately 2-, approximately 6-, and approximately 5-fold enhanced for R454D. | estrone sulfate | solute carrier family 22 member 8 | Rattus norvegicus |
| 6 | The uptakes of p-aminohippurate (PAH), estrone sulfate, and ochratoxin A were approximately 10-, approximately 48-, and approximately 32-fold enhanced in oocytes expressing rOAT3 and were only approximately 2-, approximately 6-, and approximately 5-fold enhanced for R454D. | ochratoxin A | solute carrier family 22 member 8 | Rattus norvegicus |
| 7 | Interestingly, the charge specificity of the double mutant, R454DK370A, was reversed in comparison to rOAT3-R454DK370A preferentially transported the organic cation, MPP(+), in comparison to PAH (MPP(+) uptake/PAH uptake = 3.21 for the double mutant vs 0.037 for rOAT3). | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 8 | Interestingly, the charge specificity of the double mutant, R454DK370A, was reversed in comparison to rOAT3-R454DK370A preferentially transported the organic cation, MPP(+), in comparison to PAH (MPP(+) uptake/PAH uptake = 3.21 for the double mutant vs 0.037 for rOAT3). | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 9 | Interestingly, the charge specificity of the double mutant, R454DK370A, was reversed in comparison to rOAT3-R454DK370A preferentially transported the organic cation, MPP(+), in comparison to PAH (MPP(+) uptake/PAH uptake = 3.21 for the double mutant vs 0.037 for rOAT3). | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 10 | Interestingly, the charge specificity of the double mutant, R454DK370A, was reversed in comparison to rOAT3-R454DK370A preferentially transported the organic cation, MPP(+), in comparison to PAH (MPP(+) uptake/PAH uptake = 3.21 for the double mutant vs 0.037 for rOAT3). | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 11 | These data indicate that arginine 454 and lysine 370 are essential for the anion specificity of rOAT3. | Arginine | solute carrier family 22 member 8 | Rattus norvegicus |
| 12 | These data indicate that arginine 454 and lysine 370 are essential for the anion specificity of rOAT3. | Lysine | solute carrier family 22 member 8 | Rattus norvegicus |