Pub. Date : 2002 Jul
PMID : 12089366
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Compared with mock, S2 rOAT1 and S2 rOAT3 exhibited higher levels of IS uptake, which was inhibited by probenecid and cilastatin, organic anion transport inhibitors. | Probenecid | solute carrier family 22 member 8 | Rattus norvegicus |
| 2 | Compared with mock, S2 rOAT1 and S2 rOAT3 exhibited higher levels of IS uptake, which was inhibited by probenecid and cilastatin, organic anion transport inhibitors. | Cilastatin | solute carrier family 22 member 8 | Rattus norvegicus |
| 3 | The addition of IS induced a decrease in the viability of S2 rOAT1 and S2 rOAT3 as compared with the mock, which was rescued by probenecid. | Probenecid | solute carrier family 22 member 8 | Rattus norvegicus |
| 4 | These results suggest that rOAT1 and rOAT3 play an important role in the transcellular transport of IS and the induction of its nephrotoxicity. | Indican | solute carrier family 22 member 8 | Rattus norvegicus |