Pub. Date : 2004 Nov
PMID : 15389674
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroid plexus. | 2,4-Dichlorophenoxyacetic Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 2 | The purpose of the present study is to examine whether organic anion transporter 3 (Oat3; Slc22a8) is solely responsible for the uptake of 2,4-D by the isolated rat choroid plexus (CP). | 2,4-Dichlorophenoxyacetic Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 3 | The purpose of the present study is to examine whether organic anion transporter 3 (Oat3; Slc22a8) is solely responsible for the uptake of 2,4-D by the isolated rat choroid plexus (CP). | 2,4-Dichlorophenoxyacetic Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 4 | The purpose of the present study is to examine whether organic anion transporter 3 (Oat3; Slc22a8) is solely responsible for the uptake of 2,4-D by the isolated rat choroid plexus (CP). | 2,4-Dichlorophenoxyacetic Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 5 | The basal-to-apical transport of 2,4-D in rOat3-LLC was saturable with a K(m) value of 20 microM. | 2,4-Dichlorophenoxyacetic Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 6 | Probenecid and substrates of rOat3, such as p-aminohippurate, benzylpenicillin, and cimetidine, inhibited the uptake of 2,4-D by the isolated rat CP. | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 7 | Probenecid and substrates of rOat3, such as p-aminohippurate, benzylpenicillin, and cimetidine, inhibited the uptake of 2,4-D by the isolated rat CP. | Penicillin G | solute carrier family 22 member 8 | Rattus norvegicus |
| 8 | Probenecid and substrates of rOat3, such as p-aminohippurate, benzylpenicillin, and cimetidine, inhibited the uptake of 2,4-D by the isolated rat CP. | Cimetidine | solute carrier family 22 member 8 | Rattus norvegicus |
| 9 | Probenecid and substrates of rOat3, such as p-aminohippurate, benzylpenicillin, and cimetidine, inhibited the uptake of 2,4-D by the isolated rat CP. | 2,4-Dichlorophenoxyacetic Acid | solute carrier family 22 member 8 | Rattus norvegicus |
| 10 | Their K(i) values were comparable with those for the uptake of benzylpenicillin by the isolated rat CP, which is mainly mediated by rOat3. | Penicillin G | solute carrier family 22 member 8 | Rattus norvegicus |