Pub. Date : 2002 May
PMID : 11967025
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rat organic anion transporter 3 (rOAT3)-expressing Xenopus laevis oocyte system was used for measuring [3H]indoxyl sulfate uptake activity. | [3h]indoxyl sulfate | solute carrier family 22 member 8 | Rattus norvegicus |
| 2 | rOAT3-expressing oocytes exhibited uptake of [3H]indoxyl sulfate by rOAT3 (Km = 158 micromol/L). | [3h]indoxyl sulfate | solute carrier family 22 member 8 | Rattus norvegicus |
| 3 | rOAT3-expressing oocytes exhibited uptake of [3H]indoxyl sulfate by rOAT3 (Km = 158 micromol/L). | [3h]indoxyl sulfate | solute carrier family 22 member 8 | Rattus norvegicus |
| 4 | Moreover, a number of uremic toxins inhibited the uptake of [3H]indoxyl sulfate by rOAT3. | [3h]indoxyl sulfate | solute carrier family 22 member 8 | Rattus norvegicus |
| 5 | CONCLUSIONS: These results suggest that rOAT3 is responsible for the renal uptake of indoxyl sulfate, and uremic toxins share the transport mechanism for indoxyl sulfate. | Indican | solute carrier family 22 member 8 | Rattus norvegicus |
| 6 | CONCLUSIONS: These results suggest that rOAT3 is responsible for the renal uptake of indoxyl sulfate, and uremic toxins share the transport mechanism for indoxyl sulfate. | Indican | solute carrier family 22 member 8 | Rattus norvegicus |