Title : Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.

Pub. Date : 1999 May 7

PMID : 10224140






10 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. p-Aminohippuric Acid solute carrier family 22 member 8 Rattus norvegicus
2 When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. ochratoxin A solute carrier family 22 member 8 Rattus norvegicus
3 When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. estrone sulfate solute carrier family 22 member 8 Rattus norvegicus
4 When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. Cimetidine solute carrier family 22 member 8 Rattus norvegicus
5 OAT3-mediated uptake of [3H]estrone sulfate was sodium-independent. [6,7-3H] E1S solute carrier family 22 member 8 Rattus norvegicus
6 Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. Dopamine solute carrier family 22 member 8 Rattus norvegicus
7 Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. Epinephrine solute carrier family 22 member 8 Rattus norvegicus
8 Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. Norepinephrine solute carrier family 22 member 8 Rattus norvegicus
9 Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. Serotonin solute carrier family 22 member 8 Rattus norvegicus
10 Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. estrone sulfate solute carrier family 22 member 8 Rattus norvegicus