Pub. Date : 1999 May 7
PMID : 10224140
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. | p-Aminohippuric Acid | solute carrier family 22 member 8 | Rattus norvegicus |
2 | When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. | ochratoxin A | solute carrier family 22 member 8 | Rattus norvegicus |
3 | When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. | estrone sulfate | solute carrier family 22 member 8 | Rattus norvegicus |
4 | When expressed in Xenopus laevis oocytes, OAT3 mediated the uptake of organic anions, such as p-aminohippurate (Km = 65 microM), ochratoxin A (Km = 0.74 microM), and estrone sulfate (Km = 2.3 microM) and a cationic compound, cimetidine. | Cimetidine | solute carrier family 22 member 8 | Rattus norvegicus |
5 | OAT3-mediated uptake of [3H]estrone sulfate was sodium-independent. | [6,7-3H] E1S | solute carrier family 22 member 8 | Rattus norvegicus |
6 | Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. | Dopamine | solute carrier family 22 member 8 | Rattus norvegicus |
7 | Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. | Epinephrine | solute carrier family 22 member 8 | Rattus norvegicus |
8 | Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. | Norepinephrine | solute carrier family 22 member 8 | Rattus norvegicus |
9 | Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. | Serotonin | solute carrier family 22 member 8 | Rattus norvegicus |
10 | Acidic metabolites of neurotransmitters derived from dopamine, epinephrine, norepinephrine, and serotonin inhibited the uptake of estrone sulfate via OAT3. | estrone sulfate | solute carrier family 22 member 8 | Rattus norvegicus |