Pub. Date : 2003 Aug 15
PMID : 12954363
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p-Aminohippuric acid, a substrate of rat organic anion transporter1 (rOat1), and cimetidine, a substrate of rOat3, reduced the urinary excretion of phenolsulfonphthalein. | Cimetidine | solute carrier family 22 member 8 | Rattus norvegicus |
| 2 | p-Aminohippuric acid, a substrate of rat organic anion transporter1 (rOat1), and cimetidine, a substrate of rOat3, reduced the urinary excretion of phenolsulfonphthalein. | Phenolsulfonphthalein | solute carrier family 22 member 8 | Rattus norvegicus |
| 3 | We conclude that rOat1 and rOat3 are involved in the renal uptake of phenolsulfonphthalein and that phenolsulfonphthalein is a high-affinity substrate for rOat3 but is a relatively low-affinity substrate for rOat1. | Phenolsulfonphthalein | solute carrier family 22 member 8 | Rattus norvegicus |
| 4 | We conclude that rOat1 and rOat3 are involved in the renal uptake of phenolsulfonphthalein and that phenolsulfonphthalein is a high-affinity substrate for rOat3 but is a relatively low-affinity substrate for rOat1. | Phenolsulfonphthalein | solute carrier family 22 member 8 | Rattus norvegicus |