Glycine

glutamate ionotropic receptor NMDA type subunit 1 ; Homo sapiens







133 Article(s)
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1 34736958 Allosteric antagonist action at triheteromeric NMDA receptors. 2022 Jan 1 1
2 34918931 Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity. 2022 Jan 13 2
3 35217385 De novo GRIN2A variants associated with epilepsy and autism and literature review. 2022 Apr 2
4 33773999 Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors. 2021 May 15 3
5 33976221 Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation. 2021 May 11 3
6 34058193 Glycine agonism in ionotropic glutamate receptors. 2021 Aug 1 2
7 34201404 Purinergic-Glycinergic Interaction in Neurodegenerative and Neuroinflammatory Disorders of the Retina. 2021 Jun 8 3
8 34321660 Structural basis of ketamine action on human NMDA receptors. 2021 Aug 2
9 34413877 A de novo GRIN1 Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology. 2021 2
10 34504293 Allosteric coupling of sub-millisecond clamshell motions in ionotropic glutamate receptor ligand-binding domains. 2021 Sep 9 1
11 34986531 The roles of GluN3-containing N-methyl-D-aspartate receptor in central nerve system. 2021 Oct 25 1
12 31987864 PTC-174, a positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits. 2020 Aug 15 1
13 32048268 Subunit-specific effects of poricoic acid A on NMDA receptors. 2020 Apr 1
14 32389749 Negative allosteric modulation of GluN1/GluN3 NMDA receptors. 2020 Oct 1 6
15 32610085 Structural Basis of Functional Transitions in Mammalian NMDA Receptors. 2020 Jul 23 1
16 33098865 Allosteric Changes in the NMDA Receptor Associated with Calcium-Dependent Inactivation. 2020 Dec 1 3
17 33122756 The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors. 2020 Oct 29 3
18 30482727 High Conformational Variability in the GluK2 Kainate Receptor Ligand-Binding Domain. 2019 Jan 2 1
19 31202607 Lectins modulate the functional properties of GluN1/GluN3-containing NMDA receptors. 2019 Oct 2
20 31302238 Glycine transporter inhibitors: A new avenue for managing neuropathic pain. 2019 Oct 1
21 31444392 Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors. 2019 Aug 23 2
22 29681798 The LILI Motif of M3-S2 Linkers Is a Component of the NMDA Receptor Channel Gate. 2018 1
23 29887499 Glutamate and Glycine Binding to the NMDA Receptor. 2018 Jul 3 3
24 29917241 A structurally derived model of subunit-dependent NMDA receptor function. 2018 Sep 1
25 29966365 NR1 and NR3B Composed Intranuclear N-methyl-d-aspartate Receptor Complexes in Human Melanoma Cells. 2018 Jun 30 1
26 30139821 Correction to "Identification of AICP as a GluN2C-Selective N-Methyl-D-Aspartate Receptor Superagonist at the GluN1 Glycine Site". 2018 Oct 1
27 28059133 Prediction of N-Methyl-D-Aspartate Receptor GluN1-Ligand Binding Affinity by a Novel SVM-Pose/SVM-Score Combinatorial Ensemble Docking Scheme. 2017 Jan 6 1
28 28228639 GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function. 2017 Jun 1
29 28262924 2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor. 2017 Nov 1
30 28277064 Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis. 2017 Dec 4
31 28365212 Residues in the GluN1 C-terminal domain control kinetics and pharmacology of GluN1/GluN3A N-methyl-d-aspartate receptors. 2017 Jun 1
32 28378791 Computationally Discovered Potentiating Role of Glycans on NMDA Receptors. 2017 Apr 5 1
33 28468946 Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077. 2017 Jul 2
34 28514141 Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites. 2017 Aug 16 1
35 28534738 Optocontrol of glutamate receptor activity by single side-chain photoisomerization. 2017 May 23 1
36 28588066 Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site. 2017 Aug 2
37 28760974 Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits. 2017 Aug 15 1
38 26577016 Disruption of S2-M4 linker coupling reveals novel subunit-specific contributions to N-methyl-d-aspartate receptor function and ethanol sensitivity. 2016 Jun 3
39 26661043 Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors. 2016 Feb 1
40 27000430 Protons Potentiate GluN1/GluN3A Currents by Attenuating Their Desensitisation. 2016 Mar 22 2
41 27010645 Intersubunit interactions at putative sites of ethanol action in the M3 and M4 domains of the NMDA receptor GluN1 and GluN2B subunits. 2016 Jun 3
42 27270213 Single-Molecule Patch-Clamp FRET Anisotropy Microscopy Studies of NMDA Receptor Ion Channel Activation and Deactivation under Agonist Ligand Binding in Living Cells. 2016 Jul 20 1
43 27618671 Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. 2016 Sep 21 1
44 25339225 The differential contribution of GluN1 and GluN2 to the gating operation of the NMDA receptor channel. 2015 Sep 5
45 25544544 Heteromerization of ligand binding domains of N-methyl-D-aspartate receptor requires both coagonists, L-glutamate and glycine. 2015 Jan 27 3
46 25659913 Molecular dynamics study-based mechanism of nefiracetam-induced NMDA receptor potentiation. 2015 Apr 11
47 25817860 Specific Roles of NMDA Receptor Subunits in Mental Disorders. 2015 1
48 25964432 Glycine-dependent activation of NMDA receptors. 2015 Jun 2
49 26086092 Spermidine and Ca(2+), but not Na(+), can permeate NMDA receptors consisting of GluN1 and GluN2A or GluN2B in the presence of Mg(2+). 2015 Aug 7 2
50 26205290 Inhibition of glycine transporter 1: The yellow brick road to new schizophrenia therapy? 2015 1