Pub. Date : 2021 May 11
PMID : 33976221
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Receptor activation involves glycine- and glutamate-stabilized closure of the GluN1 and GluN2 subunit ligand binding domains that is allosterically regulated by the amino-terminal domain (ATD). | Glycine | glutamate ionotropic receptor NMDA type subunit 1 | Homo sapiens |
| 2 | Glycine binding to GluN1 has no detectable effect, but unlocks the receptor for activation so that glycine and glutamate together drive an altered activation trajectory that is consistent with ATD dimer separation and rotation. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 | Homo sapiens |
| 3 | Glycine binding to GluN1 has no detectable effect, but unlocks the receptor for activation so that glycine and glutamate together drive an altered activation trajectory that is consistent with ATD dimer separation and rotation. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 | Homo sapiens |