Title : Allosteric coupling of sub-millisecond clamshell motions in ionotropic glutamate receptor ligand-binding domains.

Pub. Date : 2021 Sep 9

PMID : 34504293






1 Functional Relationships(s)
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1 We uncover allosteric coupling within NMDA LBD hetero-dimers, where binding of L-glutamate to the GluN2A LBD stalls clamshell motions of the glycine-binding GluN1 LBD. Glycine glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens