Title : Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site.

Pub. Date : 2017 Aug

PMID : 28588066






2 Functional Relationships(s)
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1 Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site. Glycine glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens
2 We show that GluN1/2C superagonism of AICP and DCS is mediated by overlapping but distinct mechanisms and that AICP selectively enhances responses from recombinant GluN1/2C receptors in the presence of physiological glycine concentrations. Glycine glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens