Serine

epidermal growth factor receptor ; Homo sapiens







96 Article(s)
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1 34323489 Emerging Approaches to Overcome Acquired Drug Resistance Obstacles to Osimertinib in Non-Small-Cell Lung Cancer. 2022 Jan 27 2
2 35093568 New trend in ligand-induced EGFR trafficking: A dual-mode clathrin-mediated endocytosis model. 2022 Mar 20 1
3 33372419 Association of hOGG1-Cys variants with occurrence of p53 and EGFR deletion mutations in non-small cell lung cancer. 2021 Feb 1
4 33737524 Diverse metabolic response of cancer cells treated with a 213Bi-anti-EGFR-immunoconjugate. 2021 Mar 18 1
5 32697994 Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR. 2020 Jul 21 1
6 31173177 Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines. 2019 Aug 1
7 31221965 Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer. 2019 Jun 20 2
8 31488827 CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity. 2019 Sep 5 1
9 32923966 GPCR transactivation signalling in vascular smooth muscle cells: role of NADPH oxidases and reactive oxygen species. 2019 1
10 28899709 Phosphorylation of epidermal growth factor receptor at serine 1047 in cultured lung alveolar epithelial cells by bradykinin B2 receptor stimulation. 2018 Feb 3
11 29136465 Recent Progress of Small-Molecule Epidermal Growth Factor Receptor (EGFR) Inhibitors against C797S Resistance in Non-Small-Cell Lung Cancer. 2018 May 24 1
12 29255092 Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation. 2018 Feb 16 5
13 29805654 Cisplatin-induced non-canonical endocytosis of EGFR via p38 phosphorylation of the C-terminal region containing Ser-1015 in non-small cell lung cancer cells. 2018 Jun 8
14 28486761 Panitumumab interaction with TAS-102 leads to combinational anticancer effects via blocking of EGFR-mediated tumor response to trifluridine. 2017 Aug 1
15 29029422 Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma. 2017 Sep 12 1
16 26727965 Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells. 2016 Aug 1
17 26733497 Novel epidermal growth factor receptor pathway mediates release of human β-defensin 3 from Helicobacter pylori-infected gastric epithelial cells. 2016 Apr 2
18 26751287 The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. 2016 Feb 1
19 27169346 Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor-mediated EGFR transactivation. 2016 Oct 1
20 25701783 Role of tyrosine kinase-independent phosphorylation of EGFR with activating mutation in cisplatin-treated lung cancer cells. 2015 Mar 20 1
21 25824408 Novel roles of ginsenoside Rg3 in apoptosis through downregulation of epidermal growth factor receptor. 2015 May 25 1
22 26141950 STAT1 Activation Is Enhanced by Cisplatin and Variably Affected by EGFR Inhibition in HNSCC Cells. 2015 Sep 1
23 26211551 Role for engagement of β-arrestin2 by the transactivated EGFR in agonist-specific regulation of δ receptor activation of ERK1/2. 2015 Oct 1
24 26622773 Inhibition of p38 mitogen-activated protein kinase potentiates the apoptotic effect of berberine/tumor necrosis factor-related apoptosis-inducing ligand combination therapy. 2015 Sep 2
25 24553453 Desensitization by different strategies of epidermal growth factor receptor and ErbB4. 2014 2
26 24615012 Signal integration and gene induction by a functionally distinct STAT3 phosphoform. 2014 May 2
27 23220022 Phosphorylation of epidermal growth factor receptor at serine 1047 by MAP kinase-activated protein kinase-2 in cultured lung epithelial cells treated with flagellin. 2013 Jan 15 3
28 23822636 Inverse correlation between Thr-669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation. 2013 Oct 2
29 23839800 Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy. 2013 Sep 1
30 23897813 Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor. 2013 Sep 6 1
31 24091658 EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells. 2013 Oct 3 1
32 24240702 A novel EGFR isoform confers increased invasiveness to cancer cells. 2013 Dec 1 1
33 22464987 Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition. 2012 Oct 15 1
34 22815474 Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776. 2012 Sep 7 1
35 23178880 ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect. 2012 Dec 2
36 21188622 Gomisin N enhances TNF-α-induced apoptosis via inhibition of the NF-κB and EGFR survival pathways. 2011 Apr 2
37 21487020 Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. 2011 Jun 10 1
38 21741919 DARPP-32 increases interactions between epidermal growth factor receptor and ERBB3 to promote tumor resistance to gefitinib. 2011 Nov 1
39 20628053 Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells. 2010 Sep 10 1
40 20654626 Structure of the complex between HER2 and an antibody paratope formed by side chains from tryptophan and serine. 2010 Sep 10 1
41 20877636 Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain. 2010 Sep 22 1
42 18340549 Epidermal growth factor receptors: function modulation by phosphorylation and glycosylation interplay. 2009 Apr 2
43 19386603 ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli. 2009 Jun 26 1
44 19531499 Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041. 2009 Sep 4
45 19578043 (-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells. 2009 Sep 2
46 19615971 Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. 2009 Sep 25 2
47 19687304 TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling. 2009 Oct 1
48 18054338 The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells. 2008 May 1
49 18354494 The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS. 2008 Apr 9 1
50 18687633 Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type. 2008 Oct 1