Title : Role of tyrosine kinase-independent phosphorylation of EGFR with activating mutation in cisplatin-treated lung cancer cells.

Pub. Date : 2015 Mar 20

PMID : 25701783






1 Functional Relationships(s)
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1 In contrast to the canonical EGFR activation in which tyrosine residues are engaged, we have demonstrated that the non-canonical pathway is triggered by phosphorylation of serine and threonine residues through p38 and ERK MAPKs, respectively. Serine epidermal growth factor receptor Homo sapiens