Serine

epidermal growth factor receptor ; Homo sapiens







96 Article(s)
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51 19036157 Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells. 2008 1
52 17615294 Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption. 2007 Sep 1
53 17720156 14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase. 2007 Oct 1 1
54 16261397 Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. 2006 Mar 1
55 16540667 Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. 2006 Mar 15 1
56 16651443 Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2. 2006 May 1 2
57 16932740 p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy. 2006 Sep 20 1
58 15880609 EGFR and Her-2 regulate the constitutive activation of NF-kappaB in PC-3 prostate cancer cells. 2005 Oct 1 1
59 16015604 Independent role of phosphoinositol-3-kinase (PI3K) and casein kinase II (CK-2) in EGFR and Her-2-mediated constitutive NF-kappaB activation in prostate cancer cells. 2005 Dec 1 1
60 16113104 Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. 2005 Jul 1
61 16184431 Asp746 to glycine change may have a greater influence than Cys751 to serine change in accounting for ligand selectivity between EGFR and HER-2 at the ATP site. 2005 May 1
62 16226704 The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells. 2005 Oct 1
63 15161351 UV-radiation-induced internalization of the epidermal growth factor receptor requires distinct serine and tyrosine residues in the cytoplasmic carboxy-terminal domain. 2004 Jun 3
64 12354760 Ganglioside induces caveolin-1 redistribution and interaction with the epidermal growth factor receptor. 2002 Dec 6 3
65 11058583 Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16. 2001 Jan 19 1
66 11330837 Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer. 2001 Feb 3
67 10347170 Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation. 1999 Jun 4 2
68 10601235 Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt. 1999 Dec 24 3
69 9346957 The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway. 1997 Oct 31 3
70 8700533 HER-2/c-erbB2 is phosphorylated by calmodulin-dependent protein kinase II on a single site in the cytoplasmic tail at threonine-1172. 1996 Jun 20 2
71 8844333 Regulation of connexin43 function by activated tyrosine protein kinases. 1996 Aug 1
72 7536439 In vivo and in vitro serine/threonine phosphorylations of epidermal growth factor receptor upon entry into the cell cycle. 1995 Jan 3
73 7540771 Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. 1995 Jun 23 1
74 8545122 The epidermal growth factor receptor is covalently linked to ubiquitin. 1995 Dec 21 2
75 8555962 Analysis of the protein kinase activity of moss phytochrome expressed in fibroblast cell culture. 1995 1
76 7505275 Calphostin-C stimulates epidermal growth factor receptor phosphorylation and internalization via light-dependent mechanism. 1994 Jan 2
77 7507488 GM3 directly inhibits tyrosine phosphorylation and de-N-acetyl-GM3 directly enhances serine phosphorylation of epidermal growth factor receptor, independently of receptor-receptor interaction. 1994 Jan 21 1
78 7523156 Cross talk of tumor necrosis factor-alpha and epidermal growth factor in human microvascular endothelial cells. 1994 Oct 1
79 7523189 Autophosphorylation-activated protein kinase inactivates the protein tyrosine phosphatase activity of protein phosphatase 2A. 1994 Oct 3 1
80 7812043 Mutation of proline-1003 to glycine in the epidermal growth factor (EGF) receptor enhances responsiveness to EGF. 1994 Jul 2
81 7971947 Comparison of conservation within and between the Ser/Thr and Tyr protein kinase family: proposed model for the catalytic domain of the epidermal growth factor receptor. 1994 Jul 1
82 8106561 Loss of cytotoxic effect of epidermal growth factor (EGF) on EGF receptor overexpressing cells is associated with attenuation of EGF receptor tyrosine kinase activity. 1994 Feb 1
83 1349014 Increased oncogenic potential of ErbB is associated with the loss of a COOH-terminal domain serine phosphorylation site. 1992 Apr 25 2
84 1379601 Signal transduction by the epidermal growth factor receptor is attenuated by a COOH-terminal domain serine phosphorylation site. 1992 Aug 15 1
85 1480174 Mutational removal of the major site of serine phosphorylation of the epidermal growth factor receptor causes potentiation of signal transduction: role of receptor down-regulation. 1992 Nov 3
86 1657956 Okadaic acid-induced hyperphosphorylation of the epidermal growth factor receptor. Comparison with receptor phosphorylation and functions affected by another tumor promoter, 12-O-tetradecanoylphorbol-13-acetate. 1991 Nov 5 1
87 1990291 Epidermal growth factor (EGF) stimulates association and kinase activity of Raf-1 with the EGF receptor. 1991 Feb 1
88 1688428 Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654. 1990 Jan 5 1
89 2105948 Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation. 1990 Feb 25 2
90 2477372 Human epidermal growth factor (EGF) receptor sequence recognized by EGF competitive monoclonal antibodies. Evidence for the localization of the EGF-binding site. 1989 Oct 15 2
91 2482148 Specific antibody response towards predicted epitopes of the epidermal growth factor receptor induced by a thermostable synthetic peptide adjuvant conjugate. 1989 Dec 1
92 3138233 Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo. 1988 Sep 15 1
93 3202876 Thapsigargin, a novel promoter, phosphorylates the epidermal growth factor receptor at threonine 669. 1988 Dec 15 1
94 2982824 Amiloride directly inhibits growth factor receptor tyrosine kinase activity. 1985 Feb 25 1
95 6092336 Diacylglycerol modulates binding and phosphorylation of the epidermal growth factor receptor. 1984 Oct 25 1
96 6321473 C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. 1984 Feb 25 1