Pub. Date : 2019 Jun 20
PMID : 31221965
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Specifically, EGFR activation branches glycolysis to the serine synthesis for nucleotide biosynthesis and redox homeostasis, whereas FGFR activation recycles lactate to fuel oxidative phosphorylation for energy generation. | Serine | epidermal growth factor receptor | Homo sapiens |
| 2 | Genetic alterations of EGFR and FGFR stratify the responsive tumors to pharmacological inhibitors that target serine synthesis and lactate fluxes, respectively. | Serine | epidermal growth factor receptor | Homo sapiens |