Title : Role for engagement of β-arrestin2 by the transactivated EGFR in agonist-specific regulation of δ receptor activation of ERK1/2.

Pub. Date : 2015 Oct

PMID : 26211551






1 Functional Relationships(s)
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1 Moreover, we demonstrated that coupling of the PKCdelta/EGFR/beta-arrestin2 transactivation pathway to delta receptor-mediated ERK1/2 activation was ligand-specific and the Ser(363) of delta receptors was crucial for ligand-specific implementation of this ERK1/2 activation pathway. Serine epidermal growth factor receptor Homo sapiens