Title : Novel epidermal growth factor receptor pathway mediates release of human β-defensin 3 from Helicobacter pylori-infected gastric epithelial cells.

Pub. Date : 2016 Apr

PMID : 26733497






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this study, we found that phosphorylation of a serine residue of EGFR via transforming growth factor beta-activated kinase-1 (TAK1), and subsequent p38alpha activation is essential for H. pylori-induced hBD3 release from gastric epithelial cells. Serine epidermal growth factor receptor Homo sapiens
2 H. pylori infection induced phosphorylation of serine residue of EGFR, and this phosphorylation was followed by internalization of EGFR; consequently, hBD3 was released at an early phase of the infection. Serine epidermal growth factor receptor Homo sapiens